Southampton's B team will face Everton, Birmingham City and Colchester United in their 2022/23 Premier League Cup campaign.
After two wins from two in Premier League 2, Dave Horseman's side will be looking to fight on another front from mid-November with the start of the 2022/23 Premier League Cup campaign.
Last season Saints faced tricky opposition in the competition, including eventual winners West Brom, Division One side Arsenal and AFC Bournemouth.
Unable to make it out of their group, Horseman and his side will be looking to improve their record this season, with the schedule as follows:
Nov 14th Everton (a)
Nov 21st Birmingham City (a)
Nov 26th Colchester United (a)
Dec 2nd Colchester United (h)
Dec 10th Everton (h)
Dec 16th Birmingham City (h)
Ticket information for each fixture will be released in due course.