The third round draws for both the Emirates FA Cup and Vitality Women's FA Cup will be made on Monday night, with Saints' Men's First Team and Women's Team ready to enter the fold.
Nathan Jones's side will be ball number 35, with the draw taking place at Anfield between 7pm and 7.30pm as teams from the Premier League and Championship entering the competition.
Saints will be targeting another strong performance in the cup, having reached the quarter-finals and semi-finals in the last two seasons.
Also beginning their FA Cup campaign will be Southampton FC Women, with Marieanne Spacey-Cale's side featuring in the southern section of the third round draw in the women's competition.
Staged from 7.30pm, Saints will be ball number 6, looking to venture further than last season's journey to the fifth round.
Click here for a full list of ball numbers and how to watch the men's FA Cup third round draw.
Click here for a full list of ball numbers and how to watch the women's FA Cup third round draw.