Ralph Hasenhüttl will be able to select from a fully fit squad ahead of a midweek trip to the capital to face Arsenal.
Saints tackle two games in the space of four days this week - both against so-called 'big six' clubs - so rotation is likely to be necessary, but the manager is pleased to be able to have a number of alternatives in various positions.
Forward pairing Danny Ings and Nathan Redmond have shaken off respective injury problems in recent weeks and have both found the net following their return to action.
"So far, surprisingly everyone tells us that they are fit and want to play again," Hasenhüttl confirmed. "It's normal that when a team is being successful that nobody thinks he's tired or wants to rest.
"We must have a look tomorrow. So far no injuries, a few tight muscles but to be honest I cannot tell you today how good players may feel tomorrow.
"Tomorrow we'll have a light session, Wednesday we'll know more. I haven't quite decided what options we'll take yet.
"We know that Reddie gives us quality from the bench, this is important. We have four fantastic players in this No.10 position, it's not easy to come in there but we like the options."