Southampton will host Brentford in the second round of the Carabao Cup, with the third round draw also made.
Ralph Hasenhüttl's side will face the Championship outfit in the final regionalised round of the competition, with the winner travelling to either West Brom or Harrogate Town in Round Three.
Having the draws conducted together will enable clubs and broadcasters to plan with additional clarity and certainty over a busy period of fixtures whilst supporters are unable to attend fixtures.
Last season, Saints beat Fulham 1-0 in round two, teeing up a first south coast derby with Portsmouth in seven years, which resulted in a comfortable 4-0 victory. Meeting holders Manchester City in the last 16, they bowed out following a 3-1 defeat at Etihad Stadium.
The second round tie at St Mary's will be played in the week commencing September 14th, with all third round ties featuring in the week commencing September 21st. Confirmed dates and times will be announced as soon as it is known.