Manager Ralph Hasenhüttl will be without midfielder Stuart Armstrong for Saturday's Premier League meeting with Watford, as he recovers from a hamstring problem sustained against Arsenal five days prior.
Sofiane Boufal has also suffered a toe injury midweek, and will be unlikely to feature, while Jannik Vestergaard has been missing through illness, ruling him out of a chunk of this week's training programme.
Encouragingly, Moussa Djenepo, who had previously been sidelined for a month with a tendon problem, has returned to action unscathed and is available for the visit of Watford.
"We have a few issues," the Austrian said. "One is Stuart Armstrong, in the last game at the end he cramped a little. He has a few problems with his hamstrings. He isn't able to play at the weekend. Maybe two weeks he is out - after Newcastle we will look again.
"Sofiane Boufal hit his toe, and hasn't been able to train for three days. It's a bit swollen still. It will be a little bit difficult for the weekend.
"Jannik was ill two days but today has been back in training. That's the latest news."