Manager Ralph Hasenhüttl has only one absentee to contend with this Saturday, as full-back Ryan Bertrand serves the final game of his three match suspension.
Boosts come in the form of Cédric and Moussa Djenepo, with the latter enjoying a small cameo during Saints' last Premier League outing at Manchester City.
Both are options for this weekend's Everton clash at St Mary's, with the manager explaining the positive impact he expects to see following both players' full return.
"So far good; Moussa [Djenepo] is back, Cédric is back," Hasenhüttl confirmed. "They can train with the team.
"We have all players on board now, so we have more options. Ryan Bertrand is still suspended but everyone else is available.
"Moussa is one of the only guys who has scored important goals for us so far, so he's a big option for the weekend.
"He gives our a game a new part, which we've missed. He can be a boost for us."