Southampton will face Portsmouth in the third round of the Carabao Cup on Tuesday 24th September, at 7.45pm BST.
Saints, who advanced past the second round with a 1-0 win at Fulham this week, were drawn away to their bitter rivals in the next stage, with the date now set.
The game will also be broadcast live on Sky Sports.
Ticket information for the match will be announced in due course.
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