Saints will be ball number four in the Emirates FA Cup semi-final draw, which takes place live on BBC One after the completion of today's other tie between Leicester and Chelsea.
The full semi-final draw numbers are as follows:
1. Tottenham Hotspur
2. Manchester United
3. Chelsea or Leicester City
Ties will be played across the weekend of 21-22 April, with a confirmed date and ticket details to follow in due course.
We’ll bring you news of our opponents as soon as it happens on our Twitter and Facebook pages, and right here at southamptonfc.com