Steven Davis and Maya Yoshida will not be travelling with the Saints squad to Newcastle this weekend, Mauricio Pellegrino has today confirmed.
Neither have recovered in time for Saturday's trip to St James' Park, and will continue with their rehab work back at Staplewood.
Long-term absentee Charlie Austin is also making progress, but again won't feature, as Saints attempt to put distance between themselves and the Premier League drop zone.
"Davo continues with his treatment," Pellegrino commented. "Last week he felt something more in his hamstring, so he will be unavailable for another week.
"Also Charlie [Austin] and Maya [Yoshida], will be the other players that are out this weekend."