Southampton’s defence of the Under-21 Premier League Cup will begin on Wednesday 6th January at home to Chelsea.
The Round of 32 clash will get under way at 7.05pm GMT, with a venue still to be confirmed.
Saints enjoyed a memorable run in the competition last year – beating Blackburn Rovers in a two-legged final to lift the trophy in front of over 12,000 supporters at St Mary’s.
Martin Hunter’s side have already faced Chelsea in the Barclays Under-21 Premier League this season, picking up their first win of the campaign with an impressive 3-1 victory at Stamford Bridge.
More details will be confirmed in the near future.